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Lactiplantibacillus plantarum strains, commonly found in meat, dairy, fruits, and vegetables, are known to support gut microbiota, modulate immune function, lower blood cholesterol, and reduce cancer risk (Zare et al., 2024)
This requires finer stratification of subjects in clinical trial design, conducting subgroup analysis based on clinical phenotypes, metabolic status, and biomarker levels to screen patient populations most likely to benefit
Thereafter, 3 grams of acetyl-L-carnitine has been taken by mouth daily for 80 days
In some embodiments, the otic formulation or composition comprises about 0.6% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof
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