A 2020 systematic review and meta-analysis published in Clinical Nutrition ESPEN (Asbaghi et al., 12 randomized controlled trials) reported oral berberine supplementation produced a statistically significant weighted mean reduction of 2.07kg in body weight, 0.47 kg/m in BMI, and 1.08cm in waist circumference versus placebo
PLoS ONE 11(10):e0163907 Bjornstad P, Hughan KS, Kelsey MM, Shah A, Lynch JL, Nehus E et al (2019) 123-OR: effect of surgical vs medical therapy on diabetic kidney disease (DKD) in severely obese adolescents with type 2 diabetes (T2D)
Questions about building muscle while on GLP-1 medications are directly relevant here, since athletic body composition concerns are exactly the basis for WADA monitoring interest
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HEALDSBURG, CA - OCTOBER 9: A group of sommeliers take a vineyard tour at Robert Young Estate Winery on October 9, 2018, near Healdsburg, California
Furthermore, the microbiota produces antimicrobial substances that protect against pathogenic colonization and supports intestinal barrier maturation and immune system regulation
