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In age-related diseases and more particularly in IPF, mice treated with FOXO4-DRI display less senescent cells leading to a reduction of the progression of fibrosis 28

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water-soluble by nature, involved in formation of red blood cells, strengthening nervous system, maintaining metabolism etc

Gastrointestinal symptoms including nausea, decreased appetite, and altered bowel habitsare among the most common side effects during active treatment

Unfortunately, significant side effects such as thrombocytopenia and transient thrombocytopathy have been reported for ABT-263 (64)

Artasensi A, Pedretti A, Vistoli G, Fumagalli L