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We have already also shown a more standard mediation analysis that shows that actually the most explainable factor for the effect on MACE [major adverse cardiovascular events] in the select trial is inflammation

GLP-1 microdosing means using significantly smaller, sustained doses of GLP-1 receptor agonist medications like semaglutide or tirzepatide than whats typically recommended in the manufacturer's official dosing schedule

doi:10.3389/fendo.2018.00584 Laurindo LF, Barbalho SM, Guiguer EL, et al

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In any case, I'll be sticking with this for a while