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Based on previous studies done in mice, researchers observed that GLP-1 agonists/DPP-4 inhibitors work to reduce inflammation in the gut, so they proposed that the same mechanism may occur in humans (5, 6)
Regardless the differences in their chemical structure and metabolic pathways, gliptins as a group constitute a widely accepted therapy for the management of T2DM, usually as a second-line medication [27, 42, 153156]
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Most practitioners recommend waiting at least 4 to 8 weeks after starting your semaglutide or tirzepatide before introducing prebiotic supplements
Oral GLP-1 RA are under development to improve convenience, acceptance, and adherence and may provide an additional option to support obesity management
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