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Cerebral metabolic changes in biotinidase deficiency

Sometimes it stalls (plateaus) completely

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This damage typically arises after extended exposure and is associated with the accumulation of melanin within the retinal tissues, particularly when recommended dosages are exceeded or when treatment is prolonged

Some studies show that the brain stores mercury at 3 to 6 times the rate of the rest of the body.[ref] Recent research points to a potentially significant way that mercury causes toxicity