Metabolic syndrome, characterized by abdominal obesity, elevated triglycerides, low HDL-C, hypertension, and insulin resistance, confers increased cardiovascular risk
In this context, the practical guidance provided by the American Gastroenterological Association and the American College of Gastroenterology for the management of chronic idiopathic constipation (CIC) [93] could also inform supportive strategies in patients experiencing constipation as a side effect of semaglutide
Moderate cardiovascular exercise (walking, cycling, swimming) 3 to 5 times per week supports cardiovascular health and enhances weight loss
Published research has associated long-term GLP-1 receptor agonist use with an elevated risk of this condition in some patient populations
However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing
The STEP 8 head-to-head trial demonstrated nearly 2.5-fold greater weight loss with semaglutide (15.8% vs 6.4%) and a lower discontinuation rate (3.2% vs 12.6%)
