Key takeaways: GLP-1 agonist medications can cause many side effects
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GLP-1 receptor agonist effects, by contrast, are described as beginning within days to weeks, with appetite suppression often noticed in the first week
The longer the gap between doses, the more pronounced the appetite return
Although the hypotensive effect of GLP-1 RAs seems to be manifested by BW losing, other mechanisms not related to BW might be implied by the mediation meta-analysis, which suggests an existence of BW-independent hypotensive effect of GLP-1 RA, along with the clinical evidence of weak or no correlations, and difference in time course between BP lowering and BW reducing effects