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A particular advantage of epithelioids over other 3D culture methods is their ability to self-sustain for weeks to months without passaging, allowing slow processes to be studied without perturbation

The rational to target PD-1/PD-L1 axis in senescence is evident and the large panel of drugs approved to target this pathway will probably accelerate the development of this strategy

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Pakravan N, Waring WS, Sharma S, Ludlam C, Megson I, Bateman DN

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doi: 10.1016/j.steroids.2023.109271