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Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin

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These may include feeling full sooner during meals, less interest in snacking, or reduced cravings for sugary or highly processed foods

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Wegovy is approved for weight management and cardiovascular risk reduction, while Ozempic is only prescribed for those with type 2 diabetes at this time

Notably, five CHGA-derived and six CHGB-derived proteoforms were significantly associated with this contrast, with all chromogranin-derived peptides showing enrichment in the frail group compared to controls (Fig