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DBP showed smaller mean changes from baseline, with the largest change noted at nine months (-2.36 mmHg)

In addition, Irg1-deficient phagocytes, which cannot produce itaconate, have shown increased susceptibility to M.tb infection, with infected mice exhibiting higher bacterial loads, reduced survival, exacerbated inflammation, extensive necrotizing granuloma formation and elevated neutrophil infiltration in the lungs [104, 105]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Cortese-Krott M.M., Koning A., Kuhnle G.G.C., Nagy P., Bianco C.L., Pasch A., Wink D.A., Fukuto J.M., Jackson A.A., van Goor H., et al

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Glutathione Peroxidase can use reduced glutathione (GSH) to reduce lipid peroxides, thereby eliminating the toxic effects of free radicals