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Beyond its direct impact, CB-839, when combined with immunotherapy, has been shown to inhibit the clonal expansion and activation of CD8+ T cells in NSCLC, thereby counteracting the adverse effects associated with PD-1 immunotherapy (89)

Beijing Friendship Hospital, Capital Medical University., (17)Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing, China;, (18)Clinical Epidemiology and EBM Unit, Beijing Friendship Hospital, Capital Medical University, Beijing Clinical Research Institute, Beijing, China Background: Portal hypertension progression can be relieved after controlling the etiology of liver cirrhosis

In contrast, recent reports indicate that AMAP is cytotoxic in primary human hepatocytes or precision-cut human liver slices [30,31]

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Experimental Pathology, 38 (3), 145164