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Because of its structural difference from natural GLP-1, it is not easy to be degraded by dipeptidyl peptidase-4 (DPP-4), thus prolonging the action time

Emerging studies suggest GLP-1s may help reduce inflammation in the body, offering additional health benefits associated with inflammation

Goodman T, Hajihosseini MK

Two other pharmaceutical companies have their own oral GLP-1 drugs in the works: Orforglipron: Developed by Eli Lilly, its in Phase 3 clinical trials for treating type 2 diabetes and obesity, with an expected September 2025 completion

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Recheck HbA1c, fasting glucose, lipids, and inflammatory markers every 812 weeks to confirm ongoing metabolic benefit even if scale weight plateaus