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Long fasting periods have been shown to increase stress hormones and disrupt thyroid and reproductive hormone levels, leading to fatigue, slowed metabolism, and menstrual irregularities

For Ozempic (semaglutide for type 2 diabetes) and Rybelsus (oral semaglutide), fatigue is not as prominently featured in the adverse event tables, suggesting potential dose-dependent effects or differences related to the treatment population

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