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Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, et al

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however, the cleavage sites differed, as evidenced by the generation of distinct S2-derived proteolytic fragments To determine whether these differences in cleavage sites affected spike protein function, we assessed cellcell fusion between S protein-expressing 293 T cells pretreated with each protease and ACE2-expressing VeroE6/TMPRSS2 cells (Fig