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Using medication beyond the manufacturer's recommended timeframe may result in reduced potency, even if the solution appears normal

Semaglutide Reduces Heavy Drinking Episodes The study compared once weekly semaglutide with a placebo in individuals diagnosed with alcohol use disorder and obesity

However, we also acknowledge that liraglutide is also available as a once-weekly injection

B12 is a relatively stable compound, so its presence in the mixture doesnt negatively affect the overall shelf life of the Semaglutide

Seek urgent medical attention (A&E or call 999) if experiencing: Severe, persistent abdominal pain that is constant or worsening, particularly if localised to the upper abdomen or radiating to the back (potential pancreatitis) Persistent vomiting preventing oral fluid intake for more than 24 hours (risk of dehydration and acute kidney injury) Signs of dehydration including reduced urine output, dizziness, confusion, or rapid heartbeat Blood in vomit or stools (haematemesis or melaena) Severe allergic reactions such as facial swelling, difficulty breathing, or widespread rash Contact your GP or diabetes specialist nurse within 2448 hours for: Diarrhoea persisting beyond one week or more than 68 loose stools daily Unintentional weight loss exceeding 12 kg per week Symptoms significantly impacting daily activities or quality of life New or worsening abdominal pain that is moderate in severity Persistent nausea preventing adequate nutritional intake Symptoms of gallbladder disease including right upper quadrant pain, particularly after fatty meals Worsening vision or eye symptoms , particularly in patients with pre-existing diabetic retinopathy Routine review is appropriate for: Mild, manageable symptoms that are improving with dietary modifications Questions about symptom management strategies Discussion of dose adjustment if symptoms are troublesome but not severe If unsure about the urgency of symptoms, contact NHS 111 for advice

She recommended maintaining a body mass index (BMI) between 18.5 and 24.8, ideally with regular exercise