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Manessis, F
Nat Rev Drug Discovery (2022) 21:20123
Appetite Regulation: Semaglutide mimics the action of the GLP-1 hormone, which helps regulate appetite
As a result, the likelihood of H 2 O covering the selenium surface was diminished, thus eliminating the adverse effect of H 2 O on Hg 0 adsorption
Some studies have reported the beneficial effects of incretin mimetics as an effective therapy for hyperphagia and obesity in PWS, considering its potential effects on ghrelin suppression, central appetite suppression (through its action on pro-opiomelanocortin POMC/CART neurons and cocaine- and amphetamine-regulated transcripts in the arcuate nucleus (195),), increased energy expenditure (EE) and stimulation of insulin secretion, which could counterbalance the hypoinsulinemia reported in PWS (196200)
By promoting a more robust metabolic function, this promising compound could potentially address age-related changes in body composition and metabolism, such as increased fat tissue as fat cells grow larger
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