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These agents include Rybelsus (oral semaglutide) and the novel first-in-class dual GIP/GLP-1 receptor agonist Mounjaro (tirzepatide), which is now available for use in the management of type 2 diabetes
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GLP-1 secreted by L cells not only potentiates the glucose-induced insulin response, promotes -cell survival, slows gastric emptying (GE), and regulates energy expenditure and body weight, but also exerts neuroprotective, cardioprotective, and anti-inflammatory effects
J Nephrol 33(5):965975 Heusser K, Tank J, Diedrich A, Fischer A, Heise T, Jordan J (2023) Randomized trial comparing SGLT2 inhibition and hydrochlorothiazide on sympathetic traffic in type 2 diabetes
Bickels work had long focused on what happens when you delay rewards, so we asked, What if GLP-1s affect how the body handles alcohol? DiFeliceantonio said
Outside the current work, JR reports lecture fees from AstraZeneca and Sanofi
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