These symptoms can resemble gastroparesis, which means the stomach empties too slowly even though no physical blockage stops food from leaving the stomach
A study of 8,000 people showed: People who stayed on the medicine lost about 12% in 1 year People who stopped early lost only about 3.6% Why the difference
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Distinguishing semaglutide-related anxiety from weight-loss-induced stress (social anxiety about body changes) requires honest assessment of your baseline anxiety history
Zhu H, Zhou L, Wang Q, Cai Q, Yang F, Jin H, Chen Y, Song Y, Zhang C (2023) Glucagon-like peptide-1 receptor agonists as a disease-modifying therapy for knee osteoarthritis mediated by weight loss: findings from the Shanghai Osteoarthritis Cohort
They found that even without causing weight loss, retatrutide had anti-tumor effects that were similar to the currently used (and incredibly expensive) immunotherapy.[ref] A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Animal studies may show the mechanism