Changes in resorufin fluorescence were measured in a 96-well microtiter plates following the protocol outlined in the commercially available Cytochrome P450 2B Fluorescent Detection Kit (CYTO2B
Randomization was stratified by response to pemetrexed in combination with cisplatin induction therapy (CR or PR versus SD), disease stage (IIIb versus IV), and ECOG PS (0 versus 1)
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It has no withdrawal syndrome and no rebound hyperglycemia in non-diabetic subjects
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