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As a result, pyridoxine deficiency can lead to relevant neuropsychiatric manifestations, such as reduced neurotransmitter synthesis, depression, epilepsy, premature aging of neurons, paresthesias, cerebrovascular diseases, cognitive impairment and carpal tunnel syndrome (58) In contrast, pyridoxine may have therapeutic potential for treating depression or aggressive behavior, since pyridoxine plays a crucial role in the tryptophan-serotonin pathway (61, 62)

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Thus, you need to consume the right amount of B12 daily if you want to avoid a vitamin B12 deficiency

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Formulated with a potent blend of glutathione and niacinamide, this cream helps to brighten the complexion, reduce the appearance of dark spots and hyperpigmentation, and improve overall skin texture and elasticity