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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Brachs S., Polack J., Brachs M., et al

People with type 2 diabetes who were prescribed a GLP-1 receptor agonist, insulin or metformin and had no history of an obesity-associated cancer from March 2005 to November 2018 were included (mean age, 59.8 years

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This is theorised to be the key reason why retatrutides trial results exceed even Mounjaros impressive numbers and it is a mechanism that is explored in much more depth in the full section below

Mediat Inflamm 2016:3094642 Li H, Chen J, Li B, Fang X (2020) The protective effects of dulaglutide against advanced glycation end products (AGEs)-induced degradation of type collagen and aggrecan in human SW1353 chondrocytes