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A previous study from Mumtaz et al

S., Zhao, Z

J Biol Chem 2002

We find that these interventions can partially prevent a loss of ovarian function and functional fertility caused by the anthracycline chemotherapy drug doxorubicin (Dox), and importantly, that this protection against infertility does not come at the cost of reduced efficacy of chemotherapy against cancer cell lines in vitro or tumour models in vivo