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Ipamorelin's structure emerged from a different optimization strategyremoval of the central dipeptide from GHRP-1 combined with Aib N-terminal substitutionresulting in a pentapeptide with potency comparable to hexapeptide GHRPs but with fundamentally different selectivity

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Data availability All data generated or analyzed during this study are included in the article and Supplementary files, or available from the corresponding author on reasonable request

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