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Advise patients who have repeatedly injected into areas of lipodystrophy or localized cutaneous amyloidosis to change the injection site to unaffected areas and closely monitor for hypoglycemia

Abbreviations ATP: Adenosine triphosphates CAT: Catalase FFA: Free fatty acids GIR: Glucose infusion rate -GCS: -Glutamylcysteine synthetase -GC: -Glutamylcysteine GPX: Glutathione peroxidase GSH: Glutathione GS: Glutathione synthetase GSSG: Oxidized glutathione IR: Insulin resistance IR- : Insulin receptor -subunit IRS: Insulin receptor substrate NAD: Nicotinamide adenine dinucleotide NADPH: Nicotinamide adenine dinucleotide phosphate hydrogen NAFLD: Nonalcoholic fatty liver disease ROS: Reactive oxygen species SOD: Superoxide dismutase C: Control CG: Control + glycine SF: Sucrose-fed SFG: Sucrose-fed + glycine

Cost and availability become another key factor in reducing dietary protein intake in the aged as do perceived intolerance to certain food groups, difficulty tearing and chewing fibrous foods, as well as the fear of consuming too much fat or cholesterol

Diabetes (2010) 59(10):265361