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High-TMAO producers have reduced oral carnitine bioavailability The TMAO productivity of gut microbiota may also present a personalized bioavailability of carnitine supplementation

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Acknowledgements/Funding M

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Additionally, some IBS patientsparticularly those with IBS-C (constipation-predominant)may experience worsening of slow transit and constipation when starting GLP-1 medications, as these drugs naturally slow gastric emptying