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Over time, this leads to an accumulation of melanin in the skin that appears as dark spots or patches on the surface

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Clinical Presentation The clinical presentation of PD is typically categorized into two main groups: motor symptoms and nonmotor symptoms

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In healthy adults, the gut microbiota is dominated by five phyla: Firmicutes (79.4%), Bacteroidetes (16.9%), Actinobacteria (2.5%), Proteobacteria (1%), and Verrucomicrobia (0.1%