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Wilson disease is caused by a genetic defect that allows copper to accumulate in the liver and other organs

De Lamirande E, Gagnon C (2002) The extracellular signal-regulated kinase (ERK) pathway is involved in human sperm function and modulated by the superoxide anion

Experimental and Toxicologic Pathology, 48 (5), 439446

The function of GPX4 is precisely regulated by nuclear factor E2-related factor 2 (NRF2), a key transcription factor that activates the expression of various antioxidant genes, including those encoding GSH synthetase and superoxide dismutase (SOD), facilitating the clearance of excess ROS (Xie et al., 2016

Stanley TL, Chen CY, Branch KL, Makimura H, Grinspoon SK

It also aids in the hepatic biotransformation and detoxification process by functioning as a hydrophilic molecule that is added to other lipophilic wastes or toxins prior to their biliary evacuation