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SIRT1 inhibitor (NAM) leads to a decrease in phosphorylation of AMPK in human hepatocytes, indicating that SIRT1 stimulates AMPK (Fig

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This cohort study describe rates of and factors associated with discontinuation and subsequent reinitiation of glucagon-like peptide-1 receptor agonists among more than 125 000 adults with overweight or obesity

We did not conduct meta-analyses for severe hypoglycaemia because events were rare

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Research findings: Historical Russian clinical trials reported improved sleep efficiency and reduced sleep latency in elderly patients