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It binds to the ghrelin receptor in the hypothalamus and pituitary gland, promoting GH secretion by increasing GHRH levels and reducing somatostatin activity

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According to the World Health Organization (WHO), over 422 million people globally live with diabetes, while obesity has nearly tripled since 1975, with more than 1 billion individuals affected, significantly increasing demand for effective GLP-1-based therapeutic interventions worldwide

Following subcutaneous injection, semaglutide is absorbed slowly from the injection site, with maximum plasma concentrations typically reached within one to three days