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Antioxidants (Basel) 9:383
Cu (Cobre): El cobre es un elemento metlico con numerosas funciones biolgicas
PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells
Nevertheless, in a forced-swimming mouse model, Meldonium reduced exercise-induced mitochondrial dysfunction, oxidative damage, and apoptosis in cardiac tissue, consistent with cardioprotective potential ( In athletes, prolonged high-intensity exertion may lead to athletic heart syndrome, characterized by cardiac hypertrophy, inflammation, oxidative stress, mitochondrial dysfunction, and accumulation of acylcarnitines with disturbed substrate oxidation ( -oxidation and activating glucose-metabolic pathways (e.g., 6-phosphofructokinase and pyruvate dehydrogenase), Meldonium shifts ATP production from lipids toward carbohydrates during exercise, which may reduce oxidative stress and improve metabolic flexibility (32)
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