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Loss of endothelial cells with subendothelial expansion is an early sign of irradiation injury
Increased G6PD activity, which is the gatekeeping enzyme of the pentose phosphate pathway [69], and xanthine suggest an increased turnover rate for purine nucleosides, which may arise from the increased DNA damage from continuous exposure to tamoxifen
Beyond trying to bind tau, companies are thinking about cell-penetrating methods to block production of the protein at its source
Blood 111 (2), 905914
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