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For those with no retinopathy, tirzepatide treatment appeared to be associated with a reduction in risk of new retinopathy, and further studies will be needed to confirm this potential added benefit of tirzepatide, presumably linked to effective glycaemic control

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This suggests that the interactions between IGF-1 LR3 and IGFBPs might determine the functional outcomes of IGF-1 LR3 in specific experimental contexts

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