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A heavy stable isotope-labelled GS*-NEM was used as an internal standard in the processed samples to achieve accurate quantitation and data normalisation (Figs

Serum ALT and AST data for vehicle- and APAP-treated animals were compared to time-matched controls by one-way ANOVA with Tukeys post-hoc test using GraphPad PRISM (version 6.03 for Windows, GraphPad Software, San Diego, CA)

Impact of probe compound in MRP2 vesicular transport assays

The cream is absorbed into the skin, providing localized treatment

The body needs a certain amount of essential vitamins and minerals to perform its daily functions, but the demands of life can make it difficult to get these nutrients from diet alone

When erastin and/or the iron compound ferlixit were used to induce ferroptosis in HEY, COV318, PEO4 and A2780CP ovarian cancer cell lines, it was found that erastin treatment was accompanied by NCOA4-mediated ferritin phagocytosis and mitochondrial dysfunction in HEY cells with high intracellular unstable iron pools (58)