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[2] Given that the most broad spectrum, premier antioxidant in your body for counteracting this is glutathione, (found in every one of your cells), it is not surprising that it gets used used up or that raising levels of it can help offset the effect

57 Another study found that consumption of 320 or 640 mg of artichoke leaf extract daily for two months significantly attenuated IBS symptoms and improved quality of life

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Effect of gluthione depletion by buthione sulfoximine on rat embryonic development in vitro

Cardiovasc Drugs Ther 1991;5 Suppl 1:11-5

Glutathione: A marker and antioxidant for aging