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Despite this, the papers on this science commonly begin by reporting that the adverse effects of GLP1a are generally mild and include nausea, vomiting, reflux, gastritis, acne (non-diabetic obese women, but not men) , 11 constipation and diarrhoea

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Thiara also said they work on the stomach to decrease gastric emptying, which leads to a feeling of fullness

Semaglutide is associated with a risk of hypoglycaemia, however, due to the glucose-dependent mode-of-action of semaglutide, the risk is relatively small compared to other diabetes treatments [102]