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Histone deacetylases (HDACs) regulate two main transcription factors, PRDM16 and PGC-1, through acetylation and deacetylation, playing crucial roles in the pathophysiology of obesity

The fatty acid synthase enzyme complex catalyzes the saturated fatty acid production through the combination of acetyl-CoA and malonylCoA to form palmitate in a series of reactions requiring the consumption of ATP and input of reducing potential from NADPH [127]

Colchicine-loaded lipid bilayer-coated 50 mesoporous nanoparticles efficiently induce microtubule depolymerization upon cell uptake

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