Despite significant evidence of improvement in some ASD symptom scales, there is still a lack of evidence to justify the use of antioxidant therapies as monotherapy in individuals with ASD
NAC has been previously shown to rescue DPI-induced cell death ( 2.8 In vivo evaluation of MitoQ and DPI: tolerability and limited efficacy in NB mouse models Finally, to evaluate the efficacy of MitoQ and DPI in vivo , both drugs were administered individually and in combination to Th- MYCN transgenic NB mice
In comparison, arginine AKG is another form of arginine-containing supplement, composed of L-arginine and alpha-ketoglutarate
KoethRAWangZLevisonBSBuffaJAOrgESheehyBTet al
The slow intravenous infusion protocols used in clinical trials minimized these effects, suggesting that rapid bolus administration (which is essentially what subcutaneous injection creates) may increase the likelihood of transient side effects
Prime time for peptide-based drug discovery