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D., Wang, X., Gygi, S

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Most of the participants in this study were female, and the results may not be extended to males without future studies with more male recruitment

The mRNA levels of inflammatory factors and cell adhesion factors were increased in the DKD group compared with the CON group, including Tnf , Il1b , Il6 , Icam1 and Vcam1 , but significantly decreased after HU treatment (Figures 3AE)

[13] Overall, for the majority of users the side effects are mild and temporary, but anyone experiencing persistent or severe symptoms should seek medical attention