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The approved update to the Summary of Product Characteristics (SmPC) for Wegovy is aimed at healthcare providers, including doctors and pharmacists

doi:10.1016/j.amjmed.2023.07.016 176

Thawed tirzepatide may look fine but will have significantly reduced potency

They treated 8 pouchees with the GLP-1 drug Liraglutide (trade name Saxenda ) in a well-designed, placebo-controlled, double-blind, cross-over clinical trial and showed a 35% reduction in toilet frequency on treatment compared to placebo, a reduction in urgency and better stool consistency and the drug was safe and well tolerated

Until then, it is only available through clinical trial enrollment or compounding pharmacies (which source research-grade peptide, not FDA-approved pharmaceutical product)

Wegovy works by acting as a GLP-1 receptor agonist