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infusion of liraglutide inhibits eating in rats by directly activating hypothalamic Pomc/Cart neurons in the ARC, without activating GLP-1-producing neurons in the hindbrain, and independent of GLP-1R signaling in vagal afferents, the area postrema (AP) and the PVN [686]

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I try to gravitate towards human ones because it's a lot more relevant

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Dividing your dose is untested and unproven, and may not deliver the weight-loss results you want.