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Discovering ferroptosis-monitoring mechanisms independent of GPX4 and RTAs will provide critical guidance for developing combination therapies aimed at inducing ferroptosis in tumors

For most patients, the 24 to 48 hours following injection are when nausea, appetite suppression, and fatigue are most pronounced

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Further, in cultured cells, manipulation of GPx-1 expression specifically alters the rate of UV-induced mutagenesis