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2013, Ozcan et al

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For example, the loss of viability caused by PGC1 suppression in melanomas could be rescued by the induction of glycolysis through hypoxia-inducible factor-1a (HIF1a) [89]

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Molybdenum is an essential cofactor for several enzymes, such as xanthine oxidoreductase (XOR), which can play a central role in oncogenesis by either catalyzing the metabolic activation of carcinogenic substances or through its products (i.e., free radicals and ROS) (398)

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