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Minimize exposure to air and avoid repeated freeze-thaw cycles, as IGF-1 LR3 is sensitive to degradation from temperature cycling

Carnitine regulatory abnormalities have been attributed to diabetic complications, trauma, hemodialysis, starvation, obesity, cardiomyopathy, fasting, endocrine imbalances, medication interactions, and other conditions (Guerra et al., 2021)

Upon reperfusion, this accumulated succinate is rapidly oxidized by succinate dehydrogenase (SDH, Complex II), leading to a highly reduced coenzyme Q (CoQ) pool