Oncotarget 6:15410 Raninga PV, Di Trapani G, Vuckovic S, Tonissen KF (2016) TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-small ka, Cyrillicbeta inhibition
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442 Therefore, blocking a single metabolic pathway is often insufficient, as CSCs can shift between metabolic dependencies to evade therapeutic pressure
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