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Psychiatry 142 PietronaveS.ForteG.LocarnoD.MerlinS.ZamperoneA.NicotraG.et al (2010)

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While this persistence rate is a marked improvement over the 10% observed for obesity-indicated GLP-1s, it still leaves 76% of potential demand unrealized

Clinical trials demonstrate that GLP-1 weight loss medications, when combined with lifestyle modifications, can produce 15-20% total body weight loss over 52 weeks

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