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A 50% toxicity rate was reached at 0.94mmol/l in HepG2 and 0.68mmol/l in HepG2 ATP7B-KO cells

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Hold: Keep the dose constant across all 4 weeks rather than titrating

First injection and early protocol Initial administration: Choose injection site (abdomen, thigh, near injury site options)

People who are at a high risk of B12 deficiency, such as those who eat strict vegetarian diets, should talk to their healthcare professional about screening for this condition

In this way, there is the opportunity to minimize additional complications related to external CCAs, if the other expectations of the CCA are met