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Fortunately, theres good news for practitioners and their patients on that front

Semaglutide was initiated at 0.25 mg, with escalation every 4 weeks until the 2.4 mg target dose was reached (Figure S1)

2 A proportion of those participants would have been on blood pressure medication at the start of the trial

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However, this timing works best for individuals with healthy digestive systems who don't experience stomach sensitivity

When activated, they appear to flatten the dopamine spikes generated by alcohol, opioids, and highly palatable foods, translating into less reward andat least in rodentsless motivation to seek the substance