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The expression of MBTPS1 was downregulated

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Unlike immunosuppressive drugs, KPV reduces inflammation without compromising immune function broadly, making it a more targeted approach

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While the prescribing information for GLP-1 medications does not specifically list Crohn's disease as a contraindication, the Summary of Product Characteristics (SmPC) for these medicines does advise caution in patients with gastrointestinal disease and states they are not recommended in severe gastrointestinal disease

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