Growth-signaling caution: As an IGF-1-derived, pro-proliferative peptide, it carries the same theoretical concern about promoting growth of pre-existing abnormal tissue a genuine reason for caution, especially with any personal or family cancer history
Gomes IB, Porto ML, Santos MC, Campagnaro BP, Pereira TM, Meyrelles SS, Vasquez EC (2014) Renoprotective, anti-oxidative and anti-apoptotic effects of oral low-dose quercetin in the C57BL/6J model of diabetic nephropathy
Retatrutides 6-day half-life produces a real peak-trough curve at weekly dosing plasma roughly doubles at the injection peak versus the pre-injection trough
It also depends on how deficient you are already
Association between bariatric surgery and long-term survival
Melov S, Ravenscroft J, Malik S, Gill MS, Walker DW, et al: Extension of life-span with superoxide dismutase = catalase mimetics